Ĭertain cancer cells, in particular gastric and colon, are unique in that they have high levels of an enzyme known as V-ATPases, which help the tumor environment stay acidic. For this study, the researchers looked back, retrospectively, into medical data to find patients who received the same chemoradiotherapy and surgery and had also received omeprazole. The standard of care for advanced rectal cancer often involves chemotherapy followed by surgery. Researchers set out to learn about the effects of omeprazole on chemoradiotherapy efficacy and tumor recurrence for patients suffering from rectal cancer. The identified mechanisms include enhancing the chemosensitivity of cancer cells, treating a specific chemotherapeutic side effect, and inhibiting cancer cell migration throughout the body. Research shows that omeprazole may help fight cancer in a variety of ways. Potential Anticancer Effects of Omeprazole Let’s take a closer look at omeprazole’s anti-tumor effects. Additionally, PPIs may weaken chemo-resistant tumors when given in conjunction with cytotoxic medications. Specifically, studies have suggested that omeprazole causes cancer cell death (apoptosis) and cancer cell breakdown (autophagy). Omeprazole and other PPIs have been found to exert anticancer effects on gastric cancer cells, B-cell tumors, pancreatic cells, and hepatoblastoma cells. Status in the U.S.: Prescription (Rx) and Over-The-Counter.Classification: Proton Pump Inhibitor (PPI).Here is a quick summary of basic facts about omeprazole: It belongs to a class of medications known as proton pump inhibitors (PPI). Omeprazole is a medication used to treat conditions such as gastroesophageal reflux disease (GERD), erosive esophagitis, and stomach ulcers. Depending on your personal situation, this may give you a valuable advantage in your fight against cancer. In some cases, omeprazole can be used off-label with chemoradiotherapy to potentially overcome resistance and enhance treatment outcomes. Today, we are going to talk about the science behind omeprazole, a common heartburn medication, and how it has potential anticancer benefits. Today’s article is going to focus on a common prescription and over-the-counter medication known as omeprazole otherwise known by its brand name, Prilosec. We explained in depth the variety of potential anti-cancer benefits of each medication. We have already reviewed drugs like Ivermectin, Doxycycline, Aspirin, and Metformin. Here at AntiCancer360, we have a series of articles looking at older medications and their excellent potential for new, off-label uses in fighting cancer. There are conventional therapies that most people are familiar with, but there are also additional options to consider especially if your cancer is advanced. There are many ways to fight cancer and, hopefully, beat it into remission. When faced with a cancer diagnosis, you want to do everything you can do to both understand the condition and fight it.
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